Short answer: Yes, there's about a $200 difference.
Long answer:
You're getting paid for Veteran, Spouse, and Child ($4,098.87) plus two additional children under the age of 18 ($103.55 * 2 = $207.10), a total of $4305.97.
You will instead be getting paid for Veteran and Child ($3,877.22) plus two additional children under the age of 18 ($207.10), a total of $4,084.32.
Your VA compensation will be reduced by $221.65 by removing your wife as a dependent.
Source:
Review 2024 Veterans disability compensation rates. Use our compensation benefits rate tables to find your monthly payment amount. We base your monthly payment amount on your disability rating and details about your dependent family members.
www.va.gov